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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRC1
All Species:
6.36
Human Site:
S587
Identified Species:
14
UniProt:
O43663
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43663
NP_003972.1
620
71607
S587
S
E
F
A
K
D
P
S
L
S
D
S
S
T
V
Chimpanzee
Pan troglodytes
XP_510600
770
87232
N737
L
Q
R
N
F
S
I
N
S
V
A
S
T
Y
S
Rhesus Macaque
Macaca mulatta
XP_001098763
640
74381
R587
S
D
Y
H
S
L
S
R
R
L
L
G
E
V
E
Dog
Lupus familis
XP_849989
620
71878
S587
S
E
F
A
K
D
P
S
L
S
D
S
S
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q99K43
603
70244
K570
L
Q
H
N
C
S
I
K
S
V
A
S
T
Y
S
Rat
Rattus norvegicus
NP_001100999
606
70580
K573
L
Q
R
N
C
S
I
K
S
V
A
S
T
Y
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001073221
262
30135
L230
Q
L
E
A
R
R
A
L
N
E
A
M
C
A
E
Frog
Xenopus laevis
NP_001080868
609
71186
N574
A
Q
R
N
I
S
I
N
S
V
A
S
T
Y
S
Zebra Danio
Brachydanio rerio
NP_956528
605
70353
N572
P
Q
R
N
F
S
I
N
S
V
A
S
T
Y
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572659
607
71048
R575
G
R
P
S
T
G
S
R
N
P
Q
K
I
R
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785901
748
86941
S710
D
K
N
G
T
G
S
S
S
A
F
S
T
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.3
89.8
93
N.A.
81.2
81.2
N.A.
N.A.
28.5
61.9
59
N.A.
22.2
N.A.
N.A.
31.2
Protein Similarity:
100
78.4
92.5
95.8
N.A.
88.3
88.8
N.A.
N.A.
35.6
76.2
73.3
N.A.
43.5
N.A.
N.A.
48.1
P-Site Identity:
100
6.6
6.6
100
N.A.
6.6
6.6
N.A.
N.A.
6.6
6.6
6.6
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
26.6
20
100
N.A.
20
20
N.A.
N.A.
13.3
33.3
26.6
N.A.
6.6
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
28
0
0
10
0
0
10
55
0
0
10
0
% A
% Cys:
0
0
0
0
19
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
10
10
0
0
0
19
0
0
0
0
19
0
0
0
0
% D
% Glu:
0
19
10
0
0
0
0
0
0
10
0
0
10
0
19
% E
% Phe:
0
0
19
0
19
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
10
0
0
10
0
19
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
46
0
0
0
0
0
10
0
0
% I
% Lys:
0
10
0
0
19
0
0
19
0
0
0
10
0
0
0
% K
% Leu:
28
10
0
0
0
10
0
10
19
10
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
10
46
0
0
0
28
19
0
0
0
0
0
0
% N
% Pro:
10
0
10
0
0
0
19
0
0
10
0
0
0
0
10
% P
% Gln:
10
46
0
0
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
10
37
0
10
10
0
19
10
0
0
0
0
10
0
% R
% Ser:
28
0
0
10
10
46
28
28
55
19
0
73
19
10
46
% S
% Thr:
0
0
0
0
19
0
0
0
0
0
0
0
55
19
10
% T
% Val:
0
0
0
0
0
0
0
0
0
46
0
0
0
10
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
46
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _